Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
Konstantinos Hatzikotoulas, Lorraine Southam, Young-Chan Park, Andrei Barysenka, Ana Luiza Arruda, Norbert Bittner, Shibo Chen, Susanne Horn, Georgia Katsoula, Peter Kreitmaier, Andrew P. Morris & Eleftheria Zeggini
deCODE Genetics/Amgen, Reykjavik, Iceland
Lilja Stefansdottir, Vinicius Tragante, Daniel F. Gudbjartsson, Gudmar Thorleifsson, Kari Stefansson & Unnur Styrkarsdottir
Department of Internal Medicine, Erasmus MC Medical Center, Rotterdam, The Netherlands
Cindy G. Boer, A. G. Uitterlinden & Joyce B. J. van Meurs
Birmingham Veterans Affairs Healthcare System (BVAHS), Birmingham, AL, USA
Merry-Lynn McDonald, Alison Rocco, Vinodh Srinivasasainagendra, Daniel Dochtermann, Bitota Lukusa-Sawalena, Chelsea Nguyen, Joshua Richman & Jasvinder A. Singh
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA
Merry-Lynn McDonald & Alison Rocco
Department of Epidemiology, School of Public Health, UAB, Birmingham, AL, USA
Merry-Lynn McDonald & Jasvinder A. Singh
Department of Genetics, School of Medicine, UAB, Birmingham, AL, USA
Merry-Lynn McDonald
Wellcome Sanger Institute, Cellular Genetics Programme, Wellcome Genome Campus, Cambridge, UK
J. Patrick Pett, Ken To & Lijiang Fei
Department of Biomedical Data Sciences, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Margo Tuerlings, Rick Mulders & Ingrid Meulenbelt
Department of Biostatistics, School of Public Health, UAB, Birmingham, AL, USA
Vinodh Srinivasasainagendra & Hemant K. Tiwari
Cambridge Stem Cell Institute, University of Cambridge, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge, UK
Ken To & Lijiang Fei
Department of Surgery, University of Cambridge, Cambridge, UK
Ken To
Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tubingen, Tübingen, Germany
Amabel M. M. Tenghe
Regeneron Genetics Center, Tarrytown, NY, USA
Arthur Gilly, Manuel Allen Revez Ferreira, Aris Baras, Marcus Jones & Luca Lotta
Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Liubov Arbeeva, Yvonne M. Golightly & Amanda E. Nelson
Department of Psychiatry, The University of Hong Kong, Pok Fu Lam, Hong Kong
Lane G. Chen & Tian T. Wu
Icahn School of Medicine at Mount Sinai, New York, NY, USA
Agathe M. de Pins
Clinical Orthopaedic Research Hvidovre (CORH), Department of Orthopaedic Surgery, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
Cecilie Henkel & Kirill Gromov
Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Jonas Höijer, Marina Mola-Caminal & Karl Michaëlsson
Department of Orthopedic Surgery, Shimane University Faculty of Medicine, Izumo, Japan
Shuji Ito, Hiroshi Takuwa, Suguru Kuwata & Yuji Uchio
Laboratory for Bone and Joint Diseases, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan
Shuji Ito & Shiro Ikegawa
Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan
Shuji Ito, Xiaoxi Liu, Kohei Tomizuka, Shiro Ikegawa & Chikashi Terao
Psychiatric Genetics, Brain and Mental Health Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Penelope A. Lind & Sarah E. Medland
School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia
Penelope A. Lind & Michelle K. Lupton
School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
Penelope A. Lind
Tohoku University Graduate School of Medicine, Sendai, Japan
Aye Ko Ko Minn, Gen Tamiya & Masayuki Yamamoto
Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
Akira Narita, Takamitsu Funayama, Chinatsu Gocho, Sachiyo Sugimoto, Fuji Nagami, Mika Sakurai-Yageta, Gen Tamiya & Masayuki Yamamoto
Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
Ene Reimann, Georgi Hudjashov, Maris Teder-Laving & Reedik Mägi
Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
Micah D. Silberstein & Phil H. Lee
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Anne-Heidi Skogholt, Maiken E. Gabrielsen, Laurent Thomas, Bendik Winsvold, Maiken Gabrielsen, Kristian Hveem, Bendik S. Winsvold & John-Anker Zwart
Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA
Michelle S. Yau
School of Biomedical Sciences, The University of Hong Kong, Pok Fu Lam, Hong Kong
Ming Yue, Kathryn S. E. Cheah & You-qiang Song
Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
Wei Zhao, Jessica D. Faul, Jennifer A. Smith & David R. Weir
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA
Wei Zhao, Sharon L. R. Kardia & Jennifer A. Smith
Department of Biostatistics, UCLA Fielding School of Public Health, Los Angeles, CA, USA
Jin J. Zhou
1st Department of Orthopaedics, KAT General Hospital, Athens, Greece
George Alexiadis
Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Karina Banasik & Søren Brunak
Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, UK
Archie Campbell & Daniel McCartney
Faculty of Medical Sciences, University College London, London, UK
Jackson T. S. Cheung
Department of Clinical Immunology, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark
Joseph Dowsett, Sisse Rye Ostrowski & Erik Sørensen
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Tariq Faquih, Renée de Mutsert, Margreet Kloppenburg & Frits R. Rosendaal
Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA
Tariq Faquih
The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
Anne Marie Fenstad & Ove Nord Furnes
Danish Headache Center, Department of Neurology, Copenhagen University Hospital, Rigshospitalet – Glostrup, Glostrup, Denmark
Thomas Hansen
Department of Orthopedic Surgery, Akureyri Hospital, Akureyri, Iceland
Thorvaldur Ingvarsson
Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Thorvaldur Ingvarsson, Helgi Jonsson & Kari Stefansson
Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Jessica S. Johnson
Department of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Jessica S. Johnson
Department of Medicine, Landspitali The National University Hospital of Iceland, Reykjavik, Iceland
Helgi Jonsson
Department of Metabolism & Endocrinology, Sportology Center, Juntendo University Graduate School of Medicine, Juntendo University, Tokyo, Japan
Saori Kakehi
Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland
Juha Karjalainen, Susanna Lemmelä, Mark Daly & Aarno Palotie
Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA
Juha Karjalainen, Mark Daly & Aarno Palotie
Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA
Juha Karjalainen, Mark Daly & Aarno Palotie
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
Juha Karjalainen, Mark Daly & Aarno Palotie
Institute for Community Medicine, SHIP-KEF, University Medicine Greifswald, Greifswald, Germany
Elisa Kasbohm & Carsten Oliver Schmidt
Finnish Institute for Health and Welfare (THL), Helsinki, Finland
Susanna Lemmelä
Nuffield Department of Population Health, University of Oxford, Oxford, UK
Kuang Lin, Iona Y. Millwood, Zhengming Chen & Robin G. Walters
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Marieke Loef & Margreet Kloppenburg
Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK
Massimo Mangino
Department of Surgery, School of Medicine, UAB, Birmingham, AL, USA
Joshua Richman
Center for Primary Care & Prevention, Brown University, Pawtucket, RI, USA
Mary B. Roberts & Charles B. Eaton
Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
Kathleen A. Ryan & Braxton D. Mitchell
Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China
Dino Samartzis & Jason Pui-Yin Cheung
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA
Dino Samartzis
Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Manu Shivakumar
Research Unit for Musculoskeletal Function and Physiotherapy, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
Søren T. Skou
The Research and Implementation Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospitals, Slagelse, Denmark
Søren T. Skou
Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK
Ken Suzuki & Andrew P. Morris
Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Ken Suzuki
Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan
Ken Suzuki
Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
Laurent Thomas
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA
Constance Turman & Peter Kraft
Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany
Stefan Weiss & Georg Homuth
4th Psychiatric Department, Dromokaiteio Psychiatric Hospital, Haidari, Athens, Greece
Eleni Zengini
Genomic Medicine Institute, Geisinger Health System, Danville, PA, USA
Yanfei Zhang & Ming Ta Michael Lee
2nd Department of Orthopaedics, National and Kapodistrian University of Athens, Medical School, ‘Konstantopouleio’ Hospital, Athens, Greece
George Babis & George Babis
Sports Medicine Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA
Tyler Barker
Intermountain Healthcare, Precision Genomics, Salt Lake City, UT, USA
Tyler Barker
Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA
Tyler Barker
Department of Genomic Health, Geisinger, Danville, PA, USA
David J. Carey & Diane T. Smelser
Department of Family Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USA
Charles B. Eaton
Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA
Charles B. Eaton
Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark
Christian Erikstrup
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Christian Erikstrup
Department of Clinical Medicine, University of Bergen, Bergen, Norway
Ove Nord Furnes
University of Nebraska Medical Center, Omaha, NE, USA
Yvonne M. Golightly
School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland
Daniel F. Gudbjartsson
Orthopedics, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Nils P. Hailer
MRC Human Genetics Unit IGC, University of Edinburgh, Edinburgh, UK
Caroline Hayward
Department of Epidemiology and Public Health, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
Marc C. Hochberg
Department of Psychiatry, Yale School of Medicine, Yale University, New Haven, CT, USA
Laura M. Huckins
HUNT Research Center, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Levanger, Norway
Kristian Hveem
Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway
Kristian Hveem
Department of Medicine for Orthopaedics and Motor Organ, Sportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan
Muneaki Ishijima
Faculty of Human Sciences, Shimane University, Matsue, Japan
Minoru Isomura
Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA
Jae H. Kang
Department of Orthopedic Surgery, Matsue Red Cross Hospital, Matsue, Japan
Nobuyuki Kumahashi
Department of Psychiatry, Harvard Medical School, Boston, USA
Phil H. Lee
Blizard Institute, Queen Mary University of London, London, UK
David A. van Heel, Robin Lerner & David A. van Heel
Department of Epidemiology & Biostatistics, School of Public Health, Peking University, Beijing, China
Liming Li
Peking University Center for Public Health and Epidemic Preparedness & Response, Beijing, China
Liming Li
Musculoskeletal Institute, Geisinger, Danville, PA, USA
Steve A. Lietman
Neurogenetics and Dementia, Brain and Mental Health Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Michelle K. Lupton
School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia
Michelle K. Lupton
Genetic Epidemiology, Brain and Mental Health Research Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Nicholas G. Martin
Division of Rheumatology, Allergy, & Immunology, Tufts Medical Center, Boston, MA, USA
Timothy E. McAlindon
School of Psychology, University of Queensland, Brisbane, Queensland, Australia
Sarah E. Medland
Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia
Sarah E. Medland
Department of Public Health, Leiden University Medical Center, Leiden, The Netherlands
Dennis O. Mook-Kanamori
Department of Functional Pathology, Shimane University School of Medicine, Izumo, Japan
Toru Nabika
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Sisse Rye Ostrowski & Ole Birger Pedersen
Department of Clinical Immunology, Zealand University Hospital – Køge, Køge, Denmark
Ole Birger Pedersen
Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong
Pak Chung Sham
Division of Rheumatology and Clinical Immunology, Department of Medicine at the School of Medicine, UAB, Birmingham, AL, USA
Jasvinder A. Singh
Medicine Service, Michale E. DeBakey VA Medical Center, Houston, TX, USA
Jasvinder A. Singh
Department of Medicine, Baylor College of Medicine, Houston, TX, USA
Jasvinder A. Singh
Statistical Genetics Team, Center for Advanced Intelligence Project, RIKEN, Tokyo, Japan
Gen Tamiya
Department of Metabolism & Endocrinology, Sportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan
Yoshifumi Tamura
Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan
Chikashi Terao
The Department of Applied Genetics, The School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
Chikashi Terao
Clinical Academic Group: Research OsteoArthritis Denmark (CAG ROAD), Department of Orthopaedic Surgery, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
Anders Troelsen
Laboratory of Cytogenetics and Molecular Genetics, Faculty of Medicine, University of Thessaly, Larissa, Greece
Aspasia Tsezou
Statens Serum Institute, Copenhagen, Denmark
Henrik Ullum
Faculty of Medicine & Health Sciences, School of Medicine, University of Nottingham, Nottingham, UK
Ana M. Valdes
School of Medicine and Population Health, The University of Sheffield, Sheffield, UK
J. Mark Wilkinson
Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital and University of Oslo, Oslo, Norway
Bendik Winsvold, Bendik S. Winsvold & John-Anker Zwart
Department of Neurology, Oslo University Hospital, Oslo, Norway
Bendik Winsvold & Bendik S. Winsvold
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
John-Anker Zwart
Department of Medicine & Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK
Sarah A. Teichmann
TUM School of Medicine and Health, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany
Eleftheria Zeggini
Study design and project coordination: E. Zeggini. Writing group: U.S., M.-L.M., J.B.J.v.M., J.M.W., L. Southam, C.G.B., K. Hatzikotoulas, J.P.P., M.T., R. Mulders, A. Barysenka, A.L.A., V.T., A.R., N.B., S.C., S.H., V.S., Y.-C.P., L. Stefánsdóttir and E. Zeggini. Central analysis team: K. Hatzikotoulas, L. Southam, L. Stefánsdóttir, C.G.B., J.P.P., M.T., R. Mulders, A. Barysenka, A.L.A., V.T., A.R., N.B., S.C., S.H., V.S., Y.-C.P. Individual study design and principal investigators: E. Zeggini, A. Tsezou, G.B., R.G.W., Z.C., L. Li., U.S., K. Stefansson, O.B.P., S.B., H.U., C.E., E.S., S.T.S., S.R.O., A. Troelsen, R. Mägi, A.P., M.D., M.T.M.L., C. Hayward, D.R.W., S.L.R.K., K.S.E.C., Y.-q.S., J.P.-Y.C., D.A.v.H., P.C.S., K. Hveem, J.-A.Z., B.S.W., T.B., Y.T., M. Ishijima, C. Terao, S. Ikegawa, T.N., Y.U., A.E.N., Y.M.G., J.B.J.v.M., R.d.M., D.O.M.-K., P. Kraft, J.H.K., J.M.W., O.N.F., P.H.L., M.K.L., S.E.M., N.G.M., A. Baras, G. Homuth, C.O.S., K.M., M.S.-Y., F.N., G. Tamiya, M. Yamamoto, A.M.V., L.M.H., H.K.T., M.-L.M., J.A. Singh, J.R., C.B.E., M.C.H., T.E.M., B.D.M., M.K., S.A.T., I.M. and the members of the arcOGEN Consortium, ARGO Consortium, DBDS Genomic Consortium, Estonian Biobank Research Team, FinnGen, Genes & Health Research Team, HUNT All-In Pain, Million Veteran Program and Regeneron Genetics Center. Analyses, genotyping, and phenotyping in individual studies: L. Southam, E. Zengini, G.A., K. Hatzikotoulas, K.L., I.Y.M., D.F.G., L. Stefánsdóttir, V.T., G. Thorleifsson, H.J., T.I., C. Henkel, K.B., T.H., J.D., K.G., Y.Z., M.T.M.L., E.R., G. Hudjashov, M.T.-L., J.K., S.L., D.J.C., D.T.S., S.A.L., M.S., D.M., A.C., W.Z., J.D.F., J.A. Smith, T.T.W., M. Yue, L.G.C., D.S., A.-H.S., L.T., M.E.G., S. Kakehi, X.L., K. Tomizuka, M. Isomura, N.K., S. Kuwata, H.T., S. Ito, L.A., C.G.B., F.R.R., M.L., T. Faquih, C. Turman, A.M.F., M.D.S., P.A.L., M.A.R.F., L. Lotta, M.J., A.G.U., S.W., E.K., M.M.-C., J.H., N.P.H., A.N., S.S., C.G., A.K.K.M., T. Funayama, M.M., A.M.d.P., J.S.J., V.S., B.L.-S., R.L., C.N., D.D., J.J.Z., A.R., M.S.Y., K.A.R., M.B.R., K. To, J.P.P., L.F., A. Barysenka, A.L.A., A.M.M.T., N.B., S.C., S.H., P. Kreitmaier, G.K., J.T.S.C., Y.-C.P., A.G., M.T., R.M., A.P.M., K. Suzuki and the members of the arcOGEN Consortium, ARGO Consortium, DBDS Genomic Consortium, Estonian Biobank Research Team, FinnGen, Genes & Health Research Team, HUNT All-In Pain, Million Veteran Program and Regeneron Genetics Center.